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Novel Coronavirus Infection (2019-nCoV)  

On December 31, 2019, the WHO China Country Office reported pneumonia cases of unknown etiology in Wuhan, China, Hubei province.  44 cases with pneumonia were reported between 31 December 2019 and 3 January 2020.  It is stated that there is a cluster in Wuhan South China Seafood Market (a wholesale fish and livestock market selling different animal species).  In the cases, images compatible with fever, dyspnea and radiological bilateral lung pneumonic infiltration were detected.

 

The AGENT:

 

In these cases, the factor was defined as a new coronavirus (2019- nCoV) that was not detected in humans on January 7, 2020.  It is from beta-coronaviruses and is in the same family as SARS and MERS-CoV coronoviruses.

 

The source of the virus is not yet clear, but it is thought to be a wild animal.  However, transmission has been reported from person to person and in health centers.  The incubation period of the virus, the period of transmission, the rate of transmission, the course of the disease and the rate of fatality are not yet known.  Compared with the onset of the SARS and MERS-Cov epidemic, severe cases and mortality are predicted to be low.  However, our information changes every hour depending on the data flow.

 

 CLINIC:

Limited information on average incubation time is available, according to MERS-CoV and SARS-CoV epidemiology information, it is assumed that there is up to 14 days incubation time for 2019-nCoV.

 

Common symptoms of infection are respiratory symptoms, fever, cough, shortness of breath, and difficulty breathing.  In more serious cases, pneumonia, severe acute respiratory infection, kidney failure and even death may develop.

 

 DIAGNOSIS:

2019-nCoV sequence information was recently shared and PCR diagnostic tests were designed.  Laboratories are recommended to confirm by pan-coronavirus test and subsequent sequence analysis.  Serological tests are useful for confirmation of immune response against specific virus groups.  Patients meeting the case definition should be tested for 2019-nCoV.  It is recommended to study respiratory secretion samples at different times than patients who fit the case.

 

TREATMENT:

There is no specific treatment and supportive treatment is applied.  Intensive care and respiratory support are provided in severe cases.

 

PROTECTION:

The vaccine is not yet available.  Isolation methods are recommended against droplet infection.  There are no travel restrictions yet.

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